How did the Gila monster, a desert lizard that eats just five times a year, help unlock the science behind Ozempic, Wegovy and Mounjaro? In this episode of The Rest Is Science, Professor Hannah Fry and Michael Stevens (Vsauce) trace the strange journey from a molecule found in lizard venom to medicines reshaping diabetes and weight-loss treatment, exploring how GLP-1 helps regulate blood sugar, appetite and the hum of ‘food noise’. Early evidence suggests their effects may extend far beyond food, quieting cravings for alcohol and cigarettes, and even the urge to gamble. What might this reveal about the biology of wanting itself, and how much control do any of us really have over what we crave? ------------------- For more information about Cancer Research UK, their research, breakthroughs and how you can support them, visit ⁠https://www.cancerresearchuk.org/our-research/rest-is-science Cancer Research UK is a registered charity in England and Wales (1089464), Scotland (SC041666), the Isle of Man (1103) and Jersey (247). A company limited by guarantee. Registered company in England and Wales (4325234) and the Isle of Man (5713F). Registered address: 2 Redman Place, London, E20 1JQ. ------------------- Video Producer: Teo Ayodeji-Ansell Animator: Sam Benson Video & Social: Bex Tyrrell Assistant Producer: Lucy Lipscombe Producer: Simona Rata Senior Producer: Lauren Armstrong-Carter Chief Digital Officer: Samuel Oakley Exec Producer: Neil Fearn