Science says eating just one meal per day can improve your health. Learn more at https://highintensityhealth.com/OMAD ----- Sought after Functional Medicine practitioner, Jeff Grimm discusses telomere testing, aging and growth hormone. Telomeres ➢ Connect with Jeff www.bioloungepdx.com www.facebook.com/bioloungepdx https://www.instagram.com/bioloungepdx ➢ Listen to the Audio in iTunes: http://highintensityhealth.com/itunes -----------------------------------------Lets Connect-------------------------------------- ➢ Facebook https://www.facebook.com/MikeMutzelMS ➢ Listen to the Audio in iTunes: http://highintensityhealth.com/itunes ➢ Instagram https://www.instagram.com/metabolic_mike --------------------------------------Key Takeaways---------------------------------- 02:03 Vitality and Optimal Performance: Overstressing an organism accelerates ageing, disease and dysfunction. If you under stress an organism, it accelerates ageing, dysfunction. 04:07 Signs of over Doing It: Systemic markers of inflammation will appear. Over stressed people wear and tear quickly and experience joint health issues. 05:16 Low Cortisol: Often, if cortisol is high, we use adaptogens and if it is low, we use glandulars or pharmaceutical cortisol. Your body is smarter than clinicians. If you have high cortisol from too much stress, this cortisol is neurotoxic. As a protective mechanism, your body may stop making ACTH (adrenocorticotropic hormone). 08:55 Stimulating the Adrenals: ACTH (adrenocorticotropic hormone) is produced by the pituitary gland. It is the hormone that sends the signal to your adrenals to make cortisol. The axis between the hypothalamus, pituitary, and adrenal is the HPA axis. 010:31 How Old am I Biologically? 12:11 Telomeres: Telomeres are segments of repeating DNA at the end of linear chromosomes. It was thought to be useless junk. The Hayflick Limit, discovered in the 1920s, was the concept that human cells do not divide indefinitely. 14:49 Testing Telomeres: Jeff uses the same testing technology as field researchers. Flow fish cytometry looks at hundreds of millions of white blood cells called leukocytes, which live for 4 months. The test accesses their average telomere length and the percentage of critically short telomeres. 15:32 Quality and Health of Telomeres: The percentage of cells in your body that have very short telomeres is much more predictive of ageing than your average telomere length. percentage of your cells that will be immediately dead or dysfunctional. 16:43 Cellular Ageing: Jeff believes that cellular ageing is a combination of the reparative enzyme being low and the shortening of the telomere happening faster than the enzyme can keep up. 20:19 Telomeres and Chronic Disease: Cells with short telomeres die faster. When you have a lot of dead cells in an organ, it does not work well. 20:52 Positively Effecting Telomere Length: Jeff has been testing his patient’s telomeres for 5 years. 21:32 Herbs and Telomeres: 25:06 Preserving Telomeres through Meditation: Apply functional medicine principals and naturopathic lifestyle medicine: stress management, yoga, tai chi and the like. 27:18 Other Mechanisms for Increasing Telomere Length: Fish oil may help. Lowering homocysteine may also increase telomeres. Exercise increases telomere length. Vitamin D in the optimal range increases telomeres. 30:04 Testing Telomeres: Jeff uses Life Length lab based in Madrid Spain for flow fish cytometry. 30:40 Inflammation’s Role in Immunosenescence: TA-65 extract resolves certain aspects of immunosenescence. The natural killer cell expression increased significantly. Chronic unresolved inflammation causes cellular dysfunction and organ system dysfunction. 34:10 Manipulation of Growth Hormone: It can help with health optimization if the right conditions are met. Secretagogues encourage your pituitary gland to secrete growth hormone which it has stored. A drug commonly used for this is Sermorelin (growth hormone releasing hormone similar to the one produced by your body). 37:58 Impacts of Manipulating Growth Hormone: To accelerate healing short term for an injury, the Sermorelin and GHRP could have a novel application. 43:10 Head Trauma and Growth Hormone: 46:53 Jeff’s Morning Routine: He is up at 5:15 and does Ashtanga yoga for 40 minutes. 48:15 Eat Fat, Get Thin: Eat fewer refined carbohydrates and eat more vegetables. 50:25 Sleep Hygiene: 52:39 Favorite Herb, Nutrient, Botanical or Food: Green tea is a single food/nutrient that has some of the best data to reduce the physical signs and symptoms of ageing and the genesis of chronic disease. Green tea is packed with flavonols like catechins, is high in polyphenols, is loaded with theanine and even has GABA. Jeff steeps his tea gong fu style. 57:49 Jeff’s Elevator Pitch: Incentivizie food programs that promote organic sustainable farming.