Cancer is one of the most terrifying illnesses of our age - a sudden change that happens silently inside our bodies and slowly eats away at us until there’s nothing left. It’s also one of the biggest failures of the pharmaceutical age - somewhere between 90 and 97% of all cancer drugs fail at clinical trials. Which is why we’re unbelievably excited to bring you our conversation with Dr. Thomas Seyfried, Professor of Biology at Boston College who appears to be hot on the trail of a cure cancer that has nothing to do with the oncology-industrial-complex. According to the dozens of papers he and his colleagues have published over the last few decades, a strict ketogenic diet coupled to a glutamine inhibitor is sufficient to weaken cancer cells to the point that the immune system can actually clear the tumor. A recent paper from his group published in February of 2025 shows the stunning effects of his protocol in a small group of eighteen glioblastoma patients. Median survival for these patients for the last hundred years has been 12-15 months, but with Seyfried’s intervention appears to have been extended up to 84 months. That’s seven years, for those keeping score. We sit down with Seyfried to take apart his protocol, why it works for cancer, why no one’s heard if it, and how everyone has completely misunderstood what cancer actually is. MAKE HISTORY WITH US THIS SUMMER: https://demystifysci.com/demysticon-2025 PATREON https://www.patreon.com/c/demystifysci PARADIGM DRIFT https://demystifysci.com/paradigm-drift-show 00:00 Go! 00:07:33 - Reception of Metabolic Cancer Research 00:10:05 - Breakthrough in Glioblastoma Treatment 00:14:49 - Glutamine-Glutamate Cycle in Cancer 00:16:33 - Challenges and Critiques of Standard Care 00:17:43 - Barriers to Implementing Metabolic Therapies 00:24:19 - Radiation and Cancer Treatment 00:26:07 - Metabolic Approach to Cancer 00:27:30 - Evolutionary Biology's Role in Understanding Cancer 00:28:52 - Mitochondria's Role in Cellular Destiny 00:31:39 - The Oxidative Phosphorylation Process 00:35:28 - Cancer and Mitochondrial Function 00:38:43 - Cellular Electrochemical Gradients 00:41:30 - Cancer's Dependency on Fermentable Fuels 00:45:08 - Glutamine's Role in Cancer Treatment 00:52:11 - Patient Compliance and Dietary Challenges 00:55:33 - Glucose Ketone Index for Health Monitoring 01:06:48 - Fenbendazole and Cancer Research 01:10:02 - Medical Industry Business Models 01:13:27 - Diets and Nutritional Ketosis 01:17:06 - Metabolic Variability and Personalization 01:19:25 - Exercise and Metabolic Health 01:23:43 - Historical Misconceptions in Cancer Treatment 01:26:21 - Obesity and Cancer Prevention 01:28:00 - Metabolic Theories of Cancer 01:47:18 - Metastatic Cancer Origins 01:55:24 - Therapeutic and Collaborative Approaches 01:59:57 - Practical Steps and Transformations #CancerResearch, #glioblastoma, #CancerAwareness, #Oncology, #CancerTreatment, #CancerSurvivor, #FightCancer, #EndCancer, #CancerSupport, #ClinicalTrials, #CancerWarrior, #BeatCancer, #CureCancer, #CancerFighter, #StayStrong, #CancerCommunity, #philosophypodcast, #sciencepodcast, #longformpodcast ABOUS US: Anastasia completed her PhD studying bioelectricity at Columbia University. When not talking to brilliant people or making movies, she spends her time painting, reading, and guiding backcountry excursions. Shilo also did his PhD at Columbia studying the elastic properties of molecular water. When he's not in the film studio, he's exploring sound in music. They are both freelance professors at various universities. PATREON: get episodes early + join our weekly Patron Chat https://bit.ly/3lcAasB MERCH: Rock some DemystifySci gear : https://demystifysci.myspreadshop.com/all AMAZON: Do your shopping through this link: https://amzn.to/3YyoT98 DONATE: https://bit.ly/3wkPqaD SUBSTACK: https://substack.com/@UCqV4_7i9h1_V7hY48eZZSLw@demystifysci BLOG: http://DemystifySci.com/blog RSS: https://anchor.fm/s/2be66934/podcast/rss MAILING LIST: https://bit.ly/3v3kz2S SOCIAL: - Discord: https://discord.gg/MJzKT8CQub - Facebook: https://www.facebook.com/groups/DemystifySci - Instagram: https://www.instagram.com/DemystifySci/ - Twitter: https://twitter.com/DemystifySci MUSIC: -Shilo Delay: https://g.co/kgs/oty671