Matthew W. Johnson is a professor and psychedelics researcher at Johns Hopkins. Please support this podcast by checking out our sponsors: - Brave: https://brave.com/lex - Neuro: https://www.getneuro.com and use code LEX to get 15% off - Four Sigmatic: https://foursigmatic.com/lex and use code LexPod to get up to 60% off - Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Matt's Twitter: https://twitter.com/Drug_Researcher Matt's Website: https://www.hopkinsmedicine.org/profiles/results/directory/profile/0800020/matthew-johnson Study Website: https://hopkinspsychedelic.org/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ Full episodes playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 Clips playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOeciFP3CBCIEElOJeitOr41 OUTLINE: 0:00 - Introduction 2:02 - Introduction to psychedelics 18:04 - Psychedelics expand the mind 21:16 - The priors we bring to the psychedelic experience 25:11 - Elon Musk and first principles thinking 35:41 - DMT 47:03 - Joe Rogan and DMT 53:11 - The nature of drug addiction 1:07:00 - The economics of drug pricing 1:13:15 - Should we legalize all drugs? 1:25:18 - What is the most dangerous drug? 1:27:52 - Does drug prohibition work? 1:31:46 - Cocaine and sex 1:38:46 - Risky sexual decisions 1:49:43 - Psilocybin helping people quit smoking 1:56:01 - Young Jamie 2:18:09 - Participating in a study 2:25:28 - Psychedelics and the human mind 2:32:51 - The future of psychedelics 2:35:32 - Neuralink 2:45:05 - Consciousness 2:57:46 - Panpsychism 3:07:51 - Aliens and DMT 3:17:55 - Mortality 3:27:44 - Meaning of life CONNECT: - Subscribe to this YouTube channel - Twitter: https://twitter.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/LexFridmanPage - Instagram: https://www.instagram.com/lexfridman - Medium: https://medium.com/@lexfridman - Support on Patreon: https://www.patreon.com/lexfridman