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Cortisol has a very narrow therapeutic index where either too much or too little of it causes significant harm to the body.
“to me cortisol probably if you thought of it as a drug it has the narrowest therapeutic index to your point too much of it will kill you eventually and make you miserable as hell on the way and too little of it will kill you quite quickly”
The Peter Attia Drive · Jan 2020 · 1 episode · 100K views on this topicExtracted by a model; may misattribute who said what.