My guest is Dr. Matthew (Max) Krummel, PhD, professor at UCSF and one of the world’s leading immunologists. We discuss how your immune system works and how sleep, emotions, and even memories shape immune function. We also explore thymus function, its role in autoimmunity, and its potential role in combating cancer. And we discuss how the type and timing of immunization can impact health. This episode provides an actionable framework for understanding how your immune system works, which ought to benefit people of all ages and health statuses. Show notes: https://go.hubermanlab.com/zKNruC3 Pre-order Protocols: https://protocolsbook.com Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Joovv: https://joovv.com/huberman Follow Huberman Lab Website: https://www.hubermanlab.com Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab X: https://x.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Timestamps 00:00:00 Max Krummel 00:02:18 Immune System, Immunotherapy 00:08:36 Illness, Childhood & Immune System 00:13:02 Aging & Immunity, DNA Mutations 00:18:36 Sponsors: Joovv & Eight Sleep 00:21:14 Self vs Non-Self Recognition, Aging, Cancer; Immune Surveillance 00:30:11 Cancer, Immune System, Age & Measuring Change 00:35:57 Thymus, T Cells; Aging & Cancer 00:42:13 Reproduction, Aging & Immune System; Basic Research 00:47:28 Sleep & Illness Susceptibility 00:52:55 Sponsor: AG1 00:54:08 Umbilical Cord Banking; Organoids, CAR T Cells, Thymus 01:02:57 Scientific Curiosity, Failures, & Discovery 01:13:14 Spatial Biology & Immune Cells; Memory & Immune State; Stress, Meditation 01:25:00 Sponsor: Function 01:26:37 Mindset; Tissue Engineering, Peptides, Systems Biology 01:34:25 Immunizations in Childhood and Beyond 01:39:37 Pharmaceutical Companies, Public Distrust 01:49:22 Disease Risk, Immunity; Autism, Flu, 01:58:56 Biological Resilience, Cancer; Computational Research 02:08:02 Autoimmune Conditions, Asthma, IBD 02:13:34 Autoimmunity & Genetic Diversity Benefits 02:17:11 Science Communication, Max's Substack 02:24:07 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter #hubermanlab #hubermanlabpodcast Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer