Patreon: https://www.patreon.com/seanmcarroll Blog post with audio player, show notes, and transcript: https://www.preposterousuniverse.com/podcast/2025/09/15/328-mary-roach-on-replacing-parts-of-our-bodies/ Like any machine, bodies occasionally break down, and it's natural to go in search of a replacement part. Ancient societies featured simple prosthetics for teeth, noses, and limbs, while modern medicine pursues more advanced ways of replacing internal organs and microbiomes. But what is striking is not just the impressive ingenuity of our attempts to replicate human anatomy, but the surprising level of difficulty involved in doing it well. I talk with author Mary Roach about the many ways in which humans have chosen to replace bits of themselves, as told in her recent book Replaceable You: Adventures in Human Anatomy. Mary Roach received a bachelor's degree in psychology from Wesleyan University. Her books include multiple New York Times bestsellers and have appeared on numerous best-of lists. She was a guest editor in the Best American Science and Nature Writing series, and received the Rushdie Award from the Harvard Secular Society. Mindscape Podcast playlist: https://www.youtube.com/playlist?list=PLrxfgDEc2NxY_fRExpDXr87tzRbPCaA5x Sean Carroll channel: https://www.youtube.com/c/seancarroll #podcast #ideas #science #philosophy #culture