Everyone wants to slow down the signs of aging, but very few people are going about it the right way. My guest on this show - Gregory Kelly - has helped to develop several rare and powerful compounds that have scientifically shown senolytic activity, and which collectively cover a broader range of mechanisms than existing senolytic supplements on the market. The negative aspects of aging are one of the most ubiquitous challenges to quality of life. However, one thing is for sure: scientists believe that a big part of the reason we experience aging the way we do is because of stressed or worn-out cells called senescent cells. Senolytics is a term used to describe ingredients shown to help decrease these damaging senescent cells. A well-formulated senolytic's goals are similar to those of pruning a plant: support efficient use of cellular resources, encourage the regeneration of more youthful cells, and ultimately support tissue health and appearance—promoting whole-body cellular rejuvenation. Since senescent cells are experts at surviving, a senolytic formula can't rely on just a single ingredient to deliver results. Instead, a multi-pronged approach helps give the body the best opportunity to reduce its senescent cell load. His protocol, which we discuss on this show, involves a two-day rejuvenation regimen that he suggests using every month. Intermittent short-duration dosing is the most common way that senolytics are used in studies, and data suggests that it can take weeks for senescent cells to re-accumulate in the body, which is why Greg recommends this approach. So who is Greg, exactly? Dr. Gregory Kelly, a highly accomplished naturopathic physician (N.D.), has an extensive background in natural medicine and nutrition. As the Director of Product Development at Neurohacker Collective and author of the book Shape Shift, Dr. Kelly has made significant contributions to the field. He has also taught Advanced Clinical Nutrition, Counseling Skills, and Doctor-Patient Relationships at the University of Bridgeport in the College of Naturopathic Medicine, and was the editor of the journal Alternative Medicine Review. With numerous articles and more than 30 journal articles indexed on Pubmed, Dr. Kelly is a leading authority in areas such as nootropics, anti-aging and regenerative medicine, weight management, and the chronobiology of performance and health. Greg's compound, called "Senolytic" (https://bengreenfieldlife.com/qualiasenolyticpod) and made by my friends at Neurohacker Collective (https://bengreenfieldlife.com/qualiasenolyticpod). During our discussion, you'll discover: -Who is Dr. Gregory Kelly?...06:38 -The science behind cellular senescence...10:19 -The best use of senolytics...19:52 -Other strategies that can limit senescence...29:40 -Qualia Synolytic...47:48 -Polyphenols in the formula...52:39 -Adaptogens in the formula...1:05:57 -Tonic herbs in the formula...1:09:55 -The efficacy of senolytics...1:16:30 For the full episode page and shownotes, visit: https://bengreenfieldlife.com/podcast/gregory-kelly-senolytic/ Additional Resources: Ben Greenfield Website: https://bengreenfieldlife.com/ Ben Greenfield Podcast: https://bengreenfieldlife.com/podcast/ Ben Greenfield Books: https://shopbengreenfieldlife.com/collections/books Ben Greenfield Social Media: Twitter https://twitter.com/bengreenfield Instagram https://www.instagram.com/bengreenfieldfitness/ Facebook https://www.facebook.com/BGFitness TikTok https://www.tiktok.com/@bengreenfield Youtube handle: @BenGreenfieldLife #longevity #howtolivelonger #senescentcells #BenGreenfield Music courtesy of Berend Salverda Licensed https://www.pond5.com/legal/license/20180904