Your body makes its own master antioxidant — but after 40, production drops every year and most people never know it's low until something breaks. Dr. Axe walks through the clinical evidence, the exact blood marker hiding on your last lab panel, and a 4-step protocol to rebuild glutathione at the cellular level — without expensive IVs. In this episode: - Why buying glutathione capsules or IVs often misses the root cause — and what to do instead - The Baylor study where two inexpensive amino acids raised glutathione 225% and restored mitochondrial function, walking speed, and insulin sensitivity in 16 weeks - The GGT marker already on most standard liver panels and what the optimal number actually is (your doctor's "normal" range isn't the same thing) - How oxidative stress drives aging, autoimmune flares, brain fog, and rosacea — and why glutathione is the body's first line of defense - GlyNAC vs. NAC vs. liposomal glutathione: which supplement does what, at what dose, and when each is worth using - The 4-step protocol: identify your drain, add sulfur foods, get targeted blood work, and give your cells the raw materials to run their own glutathione factory Chapters 0:00 Introduction — why most people raise glutathione backwards 2:34 What glutathione actually is and why it matters 5:30 The apple analogy — oxidative stress explained 6:30 Patient case: rosacea, root cause, and the GGT marker 9:08 Clinical evidence — the Baylor 16-week GlyNAC study 11:49 5 benefits: mitochondria, liver, immune function, brain, and anti-aging 25:34 Immune function deep dive — natural killer cells and the liposomal study 31:32 GGT optimal range and what high numbers predict 37:41 NAC, GlyNAC, and liposomal glutathione — dosing and differences 47:25 The 4-step rebuild protocol 54:51 Who should use caution — cancer treatment and kidney/liver disease Resources & Links - Free Downloadable PDF for Root Cause Bloodmarkers: https://guide.thehealthinstitute.com/l-390 If this episode helped you, share it with one person who needs it — and subscribe so you never miss an episode. #Glutathione #MasterAntioxidant #CellularHealth #DrAxeShow #FunctionalMedicine Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a one-on-one consultation with a Senior Health Advisor! → http://mybloodwork.com Disclaimer: The bloodwork our team runs at mybloodwork.com covers a handful of the biomarkers listed in the guide above — including critical thyroid and metabolic markers — plus a one-on-one consultation with a Senior Health Advisor, but does NOT cover all 25. You will want to consult your primary or functional doctor for the entire list. Thank you to our sponsors! Sunlighten Sauna: https://get.sunlighten.com/axepodcast Manukora Manuka Honey: https://manukora.com/axe Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: / @drjoshaxe 🎧 Early Access! Our listeners enjoy every episode before anyone else! Tune in below and join our exclusive group of listeners → Spotify: https://bit.ly/DrJoshAxeSpotify Apple Podcast: https://apple.co/3JDvWcS Order my NEW BOOK, Heal Your Cells → healyourcellsbook.com Watch my free training on how to naturally balance your blood sugar and reverse your symptoms → http://DrAxeDiabetesClass.com Discover practical steps you can take today to start healing your thyroid naturally → http://DrAxeThyroidClass.com If you’re ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com CONNECT WITH DR. JOSH AXE Instagram → / drjoshaxe Facebook → / drjoshaxe TikTok → / thedrjoshaxeshow X → https://x.com/drjoshaxe/ LinkedIn → / joshaxe Website → http://thehealthinstitute.com Sign up for my newsletter → https://bit.ly/4oE9Jf3 Ask Dr. Axe → http://speakpipe.com/drjoshaxe DISCLAIMER This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.