In this 194th in a series of live discussions with Bret Weinstein and Heather Heying (both PhDs in Biology), we discuss the state of the world through an evolutionary lens. In this episode we discuss the 2023 Nobel Prize in Physiology or Medicine, which was awarded for nucleoside base modifications that enabled the development of mRNA vaccines against COVID-19. We discuss the innovation for which the prize was awarded, what some of the known effects are, and what has been claimed about the (lack of) effects. We review some Nature news articles, including the finding that mRNA vaccines are linked to unexpected menstrual events. And we compare the costs and benefits of eating fish, supplementing with fish oil, and pharmaceutical drugging with Vascepa, and discuss connections between the three. ***** Our sponsors: Seed: Start a new healthy habit today with Seed probiotics. Use code darkhorse at https://seed.com/darkhorse to get 25% off your first month of Seed's DS-01® Daily Synbiotic. UnCruise: Get $500 off any adventure cruise on a small ship into destinations including Galapagos, Panama, Alaska, and the San Juan Islands: https://uncruise.com/pages/darkhorse/ Mindbloom: at-home ketamine therapy. Use code DARKHORSE at www.Mindbloom.com to receive $100 off your first six session program. ***** Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com/ Heather’s newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com Our book, A Hunter-Gatherer’s Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://a.co/d/dunx3at Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org ***** Q&A Link: https://rumble.com/v3my788-your-questions-answered-bret-and-heather-194th-darkhorse-podcast-livestream.html Mentioned in this episode: Nobel press release: https://www.nobelprize.org/prizes/medicine/2023/press-release/ Chinese journalist asking Nobel committee about safety: https://x.com/refugeofsinner5/status/1709225153429737584 Nobel laureate Weissman discussing safety of mRNA shots in January 2021: https://x.com/TheChiefNerd/status/1708912252487684588 Fraiman et al 2022. Serious adverse events of special interest following mRNA COVID-19 vaccination in randomized trials in adults. Vaccine, 40(40): 5798-5805:https://www.sciencedirect.com/science/article/pii/S0264410X22010283 COVID vaccines linked to unexpected vaginal bleeding. Nature News 9-25-23:https://www.nature.com/articles/d41586-023-02996-6 Covid vaccines and safety: what the research says. Nature News Explainer 2-16-21: https://www.nature.com/articles/d41586-021-00290-x How Covid unlocked the power of RNA vaccines (“Side effects can be troubling.”). Nature News feature 1-12-21: https://www.nature.com/articles/d41586-021-00019-w Fish, fishy, and fish adjacent: https://open.substack.com/pub/naturalselections/p/fish-fishy-and-fish-adjacent Job opportunity: https://amarincorp.com/job/key-account-manager *****