Hamilton Morris is a writer, documentarian, and scientific researcher who currently studies the chemistry and pharmacology of tryptamines at the University of the Sciences in Philadelphia. Start [00:00] Alexander Shulgin [07:05] Long-term effects of psychedelics[19:37] Basic literacy in chemistry—resources. [23:28] Hamilton’s early interests [27:10] 12-year-old Hamilton and street psychedelics. [27:45] First experience with salvia [29:55] Consciousness-altering substances—misunderstandings Spirituality and psychedelics [33:18] Science and shamanism [35:06] The difference between a medicine and a poison is the dose [39:21] Recommended reading [43:35] The journalism behind Hamilton’s Pharmacopeia [46:02] Hamilton’s Pharmacopeia—recommended and most popular episodes [50:02] Journalistic integrity [59:07] Recovering from bad trips [1:01:02] A 5-MeO-DMT cautionary tale [1:05:23] Ethical questions [1:07:31] Ayahuasca [1:08:55] On psychedelic guides [1:14:02] Important self-talk [1:16:13] The power of Seinfeld after a trip [1:17:09] Ayahuasca and internal motivation [1:18:33] Zombies and Wade Davis [1:21:44] Ibogaine, addicts, and Parkinson’s disease [1:25:32] Harvesting natural compounds [1:31:25] What is (and isn’t) an alkaloid? [1:37:26] Nootropics, the Dunning-Kruger effect, and defining intelligence [1:38:58] 2CD and memory retention [1:42:41] Shifts in perspective and problem solving [1:44:33] Nicotine gum gets Hamilton’s brain in motion [1:45:05] Before- and aftereffects on cognition [1:46:32]