What if your fatigue, brain fog, or chronic symptoms aren’t a malfunction—but a misunderstood survival mechanism? In this eye-opening episode, Dr. Josh Axe explores the science behind the Cell Danger Response (CDR)—a groundbreaking explanation for why the body sometimes stays in defense mode long after a threat has passed. What you’ll learn: * What the Cell Danger Response is and why it's triggered by infection, trauma, or toxins * How mitochondria signal danger and what it means when ATP becomes an alarm * The three phases of CDR: Defense, Repair, and Reintegration—and what it takes to move forward * A framework for chronic illness that connects the dots between autoimmune disease, long COVID, autism, and more Tune in to discover how the body’s built-in healing mechanisms can get stuck—and how to finally help them reset. Whether you're managing chronic illness or supporting others in healing, this episode is packed with insights that could transform your approach to health. #cellularhealth #mitochondria #draxe -------------------- -------------------- We’ve created a full blog post that walks through the main points and insights from this episode. If you'd like to dive deeper or revisit the information later, this is a helpful resource to keep on hand. Read it here → https://thehealthinstitute.com/2025/05/31/understanding-the-cell-danger-response-a-new-lens-on-chronic-illness-and-healing/ -------------------- Staying healthy in today's world is an upstream battle. Subscribe to Wellness Weekly, your 5-minute dose of sound health advice to help you grow physically, mentally, and spiritually. Every Wednesday, you'll get: * Holistic health news & life-hacks from a biblical world view * Powerful free resources including classes, Q&As, and guides from Dr. Axe * The latest episodes of The Dr. Josh Axe Show Sign up here → https://forms.thehealthinstitute.com/l-77 -------------------- Links: https://aonm.org/wp-content/uploads/2021/07/Cell-Danger-Response-IHCAN.pdf https://www.youtube.com/watch?v=u028TAyB9S4 https://pmc.ncbi.nlm.nih.gov/articles/PMC10427836/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6627909/ https://tacanow.org/family-resources/medical-article-common-medical-issues/the-cell-danger-response-in-autism/ https://www.sciencedirect.com/science/article/pii/S1567724919302922 https://www.sciencedirect.com/science/article/pii/S1567724918301053 https://www.sciencedirect.com/science/article/pii/S1567724913002390 https://www.sciencedirect.com/science/article/abs/pii/S0028390815002129 https://watermark.silverchair.com/gkv1003.pdf https://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)30428-X https://www.sciencedirect.com/science/article/abs/pii/S0022356524183231 https://www.sciencedirect.com/science/article/pii/S1567724918301053 https://www.pnas.org/doi/abs/10.1073/pnas.1607571113 https://www.mdpi.com/2079-7737/8/2/27 https://pmc.ncbi.nlm.nih.gov/articles/PMC11336094/ https://pubmed.ncbi.nlm.nih.gov/39495479/ https://advancedbrain.com/blog/the-listening-program-safe-signal-cell-danger-response/ https://ncintegrative.org/wp-content/uploads/2024/06/Cell-Danger-Response-KING.pdf https://www.nature.com/articles/s41433-024-03091-4 https://pmc.ncbi.nlm.nih.gov/articles/PMC7735836/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7963035/ https://pmc.ncbi.nlm.nih.gov/articles/PMC5859128/ https://pmc.ncbi.nlm.nih.gov/articles/PMC4988248/ ------ Ads: Even if your bloodwork looks "normal," your symptoms could point to Cell Danger Response (CDR). Discover how to break free from CDR and unlock your full potential at https://beyondbloodwork.com/ MB01LXXC1ZF1XCT -------------------- ➕ CONNECT WITH DR. JOSH AXE Facebook → https://www.facebook.com/DrJoshAxe/ Instagram → https://www.instagram.com/drjoshaxe/ X → https://x.com/drjoshaxe/ TikTok → https://www.tiktok.com/@thedrjoshaxeshow/ Website → https://thehealthinstitute.com/ -------------------- DISCLAIMER This content is strictly the opinion of Dr. Josh Axe and is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Dr. Axe nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.