Charles Raison, M.D. is a professor at the School of Human Ecology at the University of Wisconsin-Madison and Founding Director of the Center for Compassion Studies in the College of Social and Behavioral Sciences at the University of Arizona. Dr. Raison’s research focuses on inflammation and the development of depression in response to illness and stress. He also examines the physical and behavioral effects of compassion training on the brain, inflammatory processes, and behavior as well as the effect of heat stress as a potentially therapeutic intervention major depressive disorder. EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/charles-raison?utm_source=youtube&utm_medium=youtube&utm_campaign=raison_interview "The New Mind-Body Science of Depression" Book: http://amzn.to/2pi53iL Dr. Charles Raison's Research Lab: http://www.raisonresearchgroup.com/ PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=raison_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/041-dr-charles-raison-on-depression-the-immune-brain/id818198322?i=1000532219810 Spotify: https://open.spotify.com/episode/5VBAW5kNvDnZQ7hqeWyq2d Full interview playlist: https://www.youtube.com/playlist?list=PLJEEAVzHu9KzgkQbe2Thh35VU-HCiId_s Clips playlist: https://www.youtube.com/playlist?list=PLrGxo-5Uw8gI9-1IStYEvNxVukKxZBlmi Chapters 00:00:00 - Introduction 00:00:25 - Inflammation and depression 00:04:21 - Evolutionary mechanism 00:10:46 - Genetics 00:16:42 - Obesity 00:19:12 - Inflammation and depression 00:27:31 - Exercise 00:30:11 - Hyperthermia 00:36:44 - Endorphins 00:40:08 - Cytokines 00:47:40 - Hormesis 00:51:46 - Kynurenine 00:57:38 - Heat shock proteins 01:00:08 - Repurposing ancient practices 01:11:30 - Psychedelics 01:17:10 - Meditation 01:21:50 - Antidepressants 01:29:25 - Life-style modifications for depression 01:34:14 - The Wild 5 01:36:21 - Light 01:43:14 - Bipolarism and circadian rhythm SCIENCE OF HEALTHSPAN EMAIL NEWSLETTER: Receive emailed episode notifications and regular updates on the emerging science of healthspan. https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=raison_interview SUPPORT THE CHANNEL: Many of the magnificent resources associated with the FoundMyFitness channel exist directly as a result of our premium membership. As a premium member, listeners get access to our exclusive podcast The Aliquot, monthly Q&As, a special summary of scientific research every other week called the Science Digest, and more. Sign up to become a premium member and nurture the existence of all of the otherwise free resources provided by FoundMyFitness at https://www.foundmyfitness.com/crowdsponsor?utm_source=youtube&utm_medium=youtube&utm_campaign=raison_interview Thank you for watching! SOCIALS: https://twitter.com/foundmyfitness https://facebook.com/foundmyfitness https://instagram.com/foundmyfitness PODCAST: Apple Podcasts: https://podcasts.apple.com/us/podcast/foundmyfitness/id818198322 Spotify: https://open.spotify.com/show/5QjpaU0o1Q2MkVZwwG3y7d