Join the Ultimate Human VIP community and gain exclusive access to Gary Brecka's proven wellness protocols today!: https://bit.ly/4ai0Xwg Get weekly tips on how to optimize your health and lifestyle routines - go to https://www.theultimatehuman.com/ Get more resources + information from Gary here: https://linktr.ee/thegarybrecka BODY HEALTH - USE CODE ULTIMATE10 for 10% OFF YOUR ORDER bodyhealth.com/ultimate In today’s solo episode, Gary takes you through his career journey from assessing mortality risk for life insurance companies to starting a wellness franchise. He’ll share his experiences applying his knowledge of biomarkers and genetics to treat patients by looking at the root causes of disease. He’ll discuss his decades of research, striving to add not just years to your life but life to your years. He’ll also explore the role of gene mutations and nutrient deficiencies, focusing on the MTHFR gene mutation that affects up to 44% of the population and the impact it has on our body's ability to convert folic acid into methylfolate. He discusses the wide range of issues a deficiency in methylation can lead to, including anxiety, depression, and poor gut health. Listen in as we unravel the effects of a gene mutation called COMT on conditions like high blood pressure, hypothyroidism, hypercholesterolemia, and estrogen dominance. Learn how nutrient deficiencies can be the cause of common ailments, and how supplementing with the right nutrients can help restore things like estrogen balance. Join us on this journey towards becoming an Ultimate Human. Additional Topics Covered Include: Anxiety, ADD, ADHD, OCD, Gut Health, and Brain Fog The 2 Ingredients to Avoid In Your Supplements: Folic Acid and Cyanocobalamin --------- EPISODE CHAPTERS --------- JOURNAL ARTICLES REFERENCED IN EPISODE: Associations of Depressive and Anxiety Symptoms with 24-hour Urinary Catecholamines in individuals with untreated high blood pressure: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119914/ [ncbi.nlm.nih.gov] [ncbi.nlm.nih.gov] MTR and MTRR Genes: Methylation cycle and the need for Vitamin B12: https://www.geneticlifehacks.com/mtr-and-mtrr-genes-methylation-cycle-and-the-need-for-vitamin-b12/ [geneticlifehacks.com] [geneticlifehacks.com] Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109458/ [ncbi.nlm.nih.gov] [ncbi.nlm.nih.gov] Mitochondrial translation requires folate-dependent tRNA methylation: https://pubmed.ncbi.nlm.nih.gov/29364879/ [pubmed.ncbi.nlm.nih.gov] [pubmed.ncbi.nlm.nih.gov] MTR and MTRR Genes: Methylation cycle and the need for Vitamin B12: https://www.geneticlifehacks.com/mtr-and-mtrr-genes-methylation-cycle-and-the-need-for-vitamin-b12/ [geneticlifehacks.com] [geneticlifehacks.com] On the mechanism of homocysteine pathophysiology and pathogenesis: a unifying hypothesis: https://pubmed.ncbi.nlm.nih.gov/12371153/ [pubmed.ncbi.nlm.nih.gov] [pubmed.ncbi.nlm.nih.gov] Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions. Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation. Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature.