Can your childhood trauma actually destroy your immune system? Discover how early adversity and high ACE scores trigger autoimmune diseases and chronic disease risk in adulthood. In this episode, Dr. Mark Hyman sits down with Dr. Sara Gottfried—physician, researcher, and author of The Autoimmune Cure—to explore the startling connection between adverse childhood experiences (ACEs) and long-term physical health. Using eye-opening data from the original Kaiser Permanente ACE study, they break down exactly how unresolved childhood trauma doesn't just stay in your mind—it rewires your biology, driving up your risk for autoimmune diseases, inflammation, and chronic conditions decades later. But a high ACE score is not a life sentence. Dr. Gottfried shares her personal journey of reversing her own health struggles by blending Functional Medicine with breakthrough treatments. From repairing the microbiome and utilizing elimination diets to the frontier of psychedelic-assisted therapy (like MDMA and ketamine) for trauma recovery, this conversation offers a powerful, multidimensional roadmap to truly reset your immune system and heal at the root cause. #AutoimmuneDisease #ChildhoodTrauma #FunctionalMedicine #DrSaraGottfried This episode is brought to you by Rupa Health, Cozy Earth, and Magnesium Breakthrough. Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at https://RupaHealth.com. Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to https://CozyEarth.com and use code DRHYMAN. Tackle an overlooked root cause of stress with Magnesium Breakthrough. Visit https://bioptimizers.com/hyman and use code HYMAN10 to save 10% + free gifts with purchase.