Prof. Mark Solms, a neuroscientist and psychoanalyst, discusses his groundbreaking work on consciousness, challenging conventional cortex-centric views and emphasizing the role of brainstem structures in generating consciousness and affect. MLST is sponsored by Brave: The Brave Search API covers over 20 billion webpages, built from scratch without Big Tech biases or the recent extortionate price hikes on search API access. Perfect for AI model training and retrieval augmentated generation. Try it now - get 2,000 free queries monthly at http://brave.com/api. Key points discussed: The limitations of cortex-centric approaches to consciousness studies. Evidence from decorticated animals and hydranencephalic children supporting the brainstem's role in consciousness. The relationship between homeostasis, the free energy principle, and consciousness. Critiques of behaviorism and modern theories of consciousness. The importance of subjective experience in understanding brain function. The discussion also explored broader topics: The potential impact of affect-based theories on AI development. The role of the SEEKING system in exploration and learning. Connections between neuroscience, psychoanalysis, and philosophy of mind. Challenges in studying consciousness and the limitations of current theories. Mark Solms: https://neuroscience.uct.ac.za/contacts/mark-solms Show notes and transcript: https://www.dropbox.com/scl/fo/roipwmnlfmwk2e7kivzms/ACjZF-VIGC2-Suo30KcwVV0?rlkey=53y8v2cajfcgrf17p1h7v3suz&st=z8vu81hn&dl=0 TOC (*) are best bits 00:00:00 1. Intro: Challenging vision-centric approaches to consciousness * 00:02:20 2. Evidence from decorticated animals and hydranencephalic children * 00:07:40 3. Emotional responses in hydranencephalic children 00:10:40 4. Brainstem stimulation and affective states 00:15:00 5. Brainstem's role in generating affective consciousness * 00:21:50 6. Dual-aspect monism and the mind-brain relationship 00:29:37 7. Information, affect, and the hard problem of consciousness * 00:37:25 8. Wheeler's participatory universe and Chalmers' theories 00:48:51 9. Homeostasis, free energy principle, and consciousness * 00:59:25 10. Affect, voluntary behavior, and decision-making 01:05:45 11. Psychoactive substances, REM sleep, and consciousness research 01:12:14 12. Critiquing behaviorism and modern consciousness theories * 01:24:25 13. The SEEKING system and exploration in neuroscience Refs: 1. Mark Solms' book "The Hidden Spring" [00:20:34] (MUST READ!) https://amzn.to/3XyETb3 2. Karl Friston's free energy principle [00:03:50] https://www.nature.com/articles/nrn2787 3. Hydranencephaly condition [00:07:10] https://en.wikipedia.org/wiki/Hydranencephaly 4. Periaqueductal gray (PAG) [00:08:57] https://en.wikipedia.org/wiki/Periaqueductal_gray 5. Positron Emission Tomography (PET) [00:13:52] https://en.wikipedia.org/wiki/Positron_emission_tomography 6. Paul MacLean's triune brain theory [00:03:30] https://en.wikipedia.org/wiki/Triune_brain 7. Baruch Spinoza's philosophy of mind [00:23:48] https://plato.stanford.edu/entries/spinoza-epistemology-mind 8. Claude Shannon's "A Mathematical Theory of Communication" [00:32:15] https://people.math.harvard.edu/~ctm/home/text/others/shannon/entropy/entropy.pdf 9. Francis Crick's "The Astonishing Hypothesis" [00:39:57] https://en.wikipedia.org/wiki/The_Astonishing_Hypothesis 10. Frank Jackson's Knowledge Argument [00:40:54] https://plato.stanford.edu/entries/qualia-knowledge/ 11. Mesolimbic dopamine system [01:11:51] https://en.wikipedia.org/wiki/Mesolimbic_pathway 12. Jaak Panksepp's SEEKING system [01:25:23] https://en.wikipedia.org/wiki/Jaak_Panksepp#Affective_neuroscience