Dr. Will Bulsiewicz is a gastroenterologist, New York Times bestselling author, and one of the world's preeminent authorities on gut health. We discuss the gut-immune connection, the four nutritional workhorses, circadian eating, and why healing sometimes has nothing to do with diet. Check out his 2 previous appearances on the podcast: https://youtu.be/9jDsQU1UEAo?si=WB9_UlBmGIJmHVnL https://youtu.be/EABZqi3HtRM?si=WmNmXYytseR89CYT READ MORE👉🏼http://bit.ly/richroll960 ✌🏼🌱 – Rich This Episode Is Brought To You By… Prolon: Get 15% OFF plus a FREE bonus gift👉🏼https://www.prolonlife.com/richroll OneSkin: Get 15% off using code RICHROLL👉🏼https://bit.ly/oneskinrrp Airbnb: Your home might be worth more than you think. Find out how much👉🏼https://www.airbnb.com/host Go Brewing: Use the code Rich Roll for 15% OFF👉🏼https://bit.ly/gobrewing2025 Check out all of the amazing discounts from our Sponsors👉🏼https://www.richroll.com/sponsors LISTEN / SUBSCRIBE TO THE PODCAST Apple Podcasts: http://bit.ly/rrpitunes Spotify: http://bit.ly/rrpspotify Google: http://bit.ly/rrpgooglepods Meal Planner: http://meals.richroll.com Voicing Change Book: http://richroll.com/vc Clips Channel: https://www.youtube.com/c/RichRollPodcastClips Newsletter: http://bit.ly/rollcallemail 00:00:00 Introduction 00:01:27 The Gut-Immune Connection & Chronic Disease 00:05:28 Summary of the Gut-Inflammation Link 00:06:06 Nuance: Genetics and Disease 00:06:56 Innate vs. Adaptive Immunity 00:10:47 The Gut Barrier and Immune Protection 00:12:47 Chronic Low-Grade Inflammation Symptoms 00:14:52 Medical System’s Approach & Testing Limitations 00:16:53 Microbiome Geography & Testing Challenges 00:18:02 Role of the Mucosal Layer 00:18:47 Short Chain Fatty Acids & Gut Health 00:19:40 Self-Diagnosis & Prevalence of Inflammation 00:22:37 The Microbiome as a Life Story 00:23:24 Drivers of Poor Gut Health: Food & Environment 00:24:04 Ultra-Processed Foods & Health Risks 00:26:48 Modern Lifestyle & Loneliness 00:28:31 Sponsor Break 00:31:07 Ultra-Processed Foods: Mechanisms of Harm 00:33:01 Sugar, Salt, and Fat: Microbiome Impact 00:37:59 Hyperpalatability & Overeating 00:40:36 Food Additives & Regulatory Gaps 00:45:42 Personal Agency vs. Systemic Change 00:48:04 Dietary Interventions: Where to Start? 00:52:21 The Four Nutrients: 1. Fiber 00:55:12 Prebiotic Fiber & Resistant Starch 00:57:53 Diversity of Plant Foods 00:59:21 Carnivore Diet & Fiber Debate 01:02:54 Sponsor Break 01:05:59 Short Chain Fatty Acids: Anti-Inflammatory Power 01:09:57 The Four Nutrients: 2. Polyphenols 01:15:35 The Four Nutrients: 3. Omega-3 fats 01:24:52 Seed Oils & Inflammation Debate 01:27:49 The Four Nutrients: 4. Fermented Foods 01:31:06 Recap: The Four Workhorses 01:32:08 Environment, Circadian Rhythm, and Gut Health 01:34:22 Circadian Rhythm & Morning Sunlight 01:42:22 Time-Restricted Eating & Meal Timing 01:47:45 Alcohol & Gut Barrier Disruption 01:52:19 Emotional & Spiritual Health 01:58:41 Sympathetic vs. Parasympathetic Balance 02:03:21 Trauma, Healing, and the Gut 02:09:36 Personal Story: Family, Forgiveness, and Faith 02:24:23 Conclusion: Holistic Health & Final Thoughts CONNECT WITH RICH ✩ Website - http://richroll.com​ ✩ Rich Roll Podcast - https://richroll.com/all-episodes/ ✩ Instagram - https://www.instagram.com/richroll/ ✩ Twitter - https://twitter.com/richroll ✩ Facebook - https://www.facebook.com/richrollfans ✩ Strava - https://www.strava.com/athletes/14443?oq=rich ✩ Memoir: Finding Ultra - https://www.richroll.com/shop/books/finding-ultra/ ✩ Meals - http://meals.richroll.com​ ✩ Cook - The Plantpower Way - https://www.richroll.com/shop/books/the-plantpower-way-signed/ ✩ Italian! - The Plantpower Way: Italia - https://www.richroll.com/shop/books/the-plantpower-way-italia-signed/ ✩ Support - https://www.patreon.com/richroll Thanks To The Team: Jason Camiolo, Dan Drake, Morgan McRae, Blake Curtis, Desmond Loh * * * * * NEW TO RICH? Hi I'm Rich Roll. I'm a vegan ultra-endurance athlete, author, podcaster, public speaker & wellness evangelist. But mainly I'm a dad of four. If you want to know more, visit my website or check out these two the NY Times articles: http://bit.ly/otillonyt http://bit.ly/vegansglam I LOVE MAIL! SEND IT HERE: 2630 Conejo Spectrum St. Thousand Oaks, CA 91320 #richroll #richrollpodcast