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Episode
Longevity Expert Shares Game-Changing Tips for Healthy Aging | Matt Kaeberlein, PhD
Views
26K
0.3× the show’s average
Episode26K
Show avg91K
Published
6y ago
Sep 24, 2020
Length
1h 31m
show avg 56m
From the show
Chapters
Matt Kaeberlein, PhD discusses how improving the mechanisms of aging enhance not only support longevity, but also boost immune system health. ➢Today's show is brought to you by Keto Brick! One of the best Ketogenic meal replacements out there Get started: https://www.ketobrick.com Crush your Workouts and stay hydrated this summer with the Electrolyte + Creatine Combo by MYOXCIENCE: https://bit.ly/electrolyte-stix *Save with code podcast at checkout Related Video with Dr. Peter Attia discussing autophagy and fasting: https://youtu.be/EklA1iI2Iy8 -----------------------------------------Lets Connect-------------------------------------- ➢ Facebook https://www.facebook.com/MikeMutzelMS ➢ Listen to the Audio in iTunes: https://itunes.apple.com/us/podcast/2... ➢ Instagram https://www.instagram.com/metabolic_mike ------------------------------------Show Notes--------------------------------------
- 0:00Intro
- 4:00Your risk of a severe outcome from Corona has an age-related exponential increase.
- 7:03No federal Corona funds went to the National Institute on Aging, despite the fact that age is the greatest risk factor for dying from Corona.
- 18:16Targeting the biological mechanisms of aging strengthens the immune system of older people against many illnesses.
- 19:44Biological aging can be impacted significantly. With the immune system, we can probably get a 20-year restoration of function, maybe more.
- 31:25Genes that affect aging were created to make the decision between fast reproduction/low stress resistance vs slow reproduction/high stress resistance.
- 32:14Unregulated continued expression of pathways like mTOR at high levels drives aging.
- 33:58With chronic expression of pro-growth pathways in dividing cells, your risk of developing cancer goes up dramatically.
- 35:18The continued expression of pro-growth pathways in cells in the brain and heart, is associated with higher levels of oxidative stress.
- 35:42High levels of oxidative stress largely from metabolic processes can cause cells to go into senescent state, where the cells give off pro-inflammatory signals.
- 37:05Age related increase of inflammation creates an environment that permits many of the functional declines and diseases associated with aging.
- 37:54In mice, if you clear senescent cells accumulated from aging, you see a dramatic reduction in inflammatory molecules and signaling, increased lifespan and functional improvements.
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Names dropped
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