This is a continuation of the last episode where Dr. Patrick took questions from newsletter subscribers around the on-going pandemic and tried to add value by talking about some of the recent research, among other things. Some of the topics that came up as a result of the questions submitted include: • 00:04:03 - Duration of SARS-CoV-2 immunity after infection • 00:06:37 - SARS-CoV-2 and potential immunity • 00:11:35 - Some of the main factors known to play a role in immune variation • 00:12:05 - What role genetics may play in immune function • 00:14:27 - How previous viral exposure regulates immunity | Rhonda Patrick • 00:15:05 - What cross immunity is and how it may be relevant for SARS-CoV-2 • 00:19:46 - Antibody-dependent enhancement and SARS-CoV-2 relevance • 00:21:50 - How sleep is a key regulator of immune function • 00:23:44 - Microbiome composition and immune function • 00:28:31 - The differential effects of exercise intensity and duration on immune regulation • 00:35:00 - How specific micronutrient inadequacies may promote immune dysregulation • 00:47:20 - The effect of sex hormones on immune function • 00:48:55 - How biological age may play a role in immune regulation • 00:49:46 - Controversy surrounding hypertension drugs such as ACE inhibitors and COVID-19 • 00:53:15 - ARDS and long-term lung damage You can find this episode page along with a very detailed summary with references at https://www.foundmyfitness.com/episodes/covid-19-episode-2 Chapters 00:00:00 - Introduction 00:04:03 - Infection course 00:06:37 - Immunity 00:11:35 - Risk factors 00:12:05 - Genetics 00:14:27 - Immunity 00:15:05 - Cross immunity 00:19:46 - Antibody-dependent enhancement 00:21:50 - Sleep 00:23:44 - Microbiome 00:28:31 - Exercise 00:35:00 - Diet 00:47:20 - Sex hormones 00:48:55 - Biological age 00:49:46 - Blood pressure drugs 00:53:15 - ARDS and long-term lung damage You can find the PREVIOUS episode at https://www.foundmyfitness.com/episodes/covid-19-episode-1 This episode mentions a number of genetic polymorphisms that affect viral entry into the host cell, viral replication, host immune response ranging from cytokine production to viral-induced inflammation, SNPs that affect vitamin D levels, and more. If you have used any consumer-based genetic testing services like 23andMe or Ancestry DNA we have a free viral report with these SNPs that you can check out. You can find that at https://www.foundmyfitness.com/genetics/viral. If you enjoy this content or any of the associated content, I can promise you that not only does the premium membership help bring MORE of it into the world in a broadly accessible format, that membership also comes with some really great benefits just for members. Members enjoy extra science emails twice per month, my monthly Question & Answer sessions, and a whole lot more. Support the show and get cool perks, that’s the bottom line. Head over to https://www.foundmyfitness.com/premium to learn how to get started.