My guest is Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health. We discuss how to optimize male hormones using a range of nutritional and behavioral tools, exercise and supplementation (including tongkat ali, fadogia agrestis, creatine, peptides and more). We explain how puberty and aging affect hormone levels, how to use bloodwork to monitor hormone levels, how hormone health impacts fertility, libido, hair loss and prostate health and describe behaviors that negatively impact testosterone levels. We also discuss how to approach prescription hormone therapies, including which biomarkers to monitor when using these approaches and how to optimize synergistic hormones (e.g., growth hormone and thyroid hormone) to support complete hormone health safely and rationally. Dr. Gillett offers numerous actionable tools that can be tailored to specific goals and age ranges to attain and maintain optimal levels of male hormones for overall health, well-being and longevity. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman ROKA: https://www.roka.com/huberman Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://www.insidetracker.com/huberman Huberman Lab Premium https://hubermanlab.com/premium Social & Website Instagram: https://www.instagram.com/hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://hubermanlab.com Newsletter: https://hubermanlab.com/neural-network Dr. Kyle Gillet Dr. Gillett’s clinic: https://gilletthealth.com Gillet Health YouTube channel: https://www.youtube.com/@gilletthealth6738 The Gillet Health Podcast on Spotify: https://spoti.fi/3Bu13kh The Gillet Health Podcast on Apple Podcasts: https://apple.co/3FJSCUz Instagram: https://www.Instagram.com/kylegillettmd Twitter: https://twitter.com/gilletthealth Timestamps 00:00:00 Dr. Kyle Gillett & Male Hormone Optimization 00:03:40 Thesis, ROKA, Helix Sleep, Momentous 00:07:43 Puberty: Height, Resistance Training, Childhood Obesity 00:15:14 “First” vs. “Second” Puberty 00:17:17 Hormone Optimization & Blood Work 00:22:14 Diet, Exercise, Sleep & Hormones 00:28:23 Hormones, Stress, Social Connection & Purpose 00:32:19 Hormones, Supplementation & Medication 00:34:08 Determining Individual Hormone Levels, ADAM Questionnaire 00:40:35 Libido, Masturbation, Pornography & the Dopamine “Wave Pool” 00:48:32 AG1 (Athletic Greens) 00:49:46 Sustainable Exercise Regimen for Hormone Health 00:58:12 Testosterone Replacement Therapy (TRT) 01:01:02 Supplementation: Creatine & Hair Loss, Betaine, L-Carnitine & Allicin (Garlic) 01:11:45 Vitamin D, Boron; SHBG & Free Testosterone 01:15:34 InsideTracker 01:16:39 Tongkat Ali (Eurycoma longifolia; Longjack) & Steroid Pathways 01:22:09 Fadogia Agrestis & Testosterone 01:26:32 Optimize Growth Hormone & IGF-1: Diet, Fasting, Supplements & Exercise 01:31:52 Optimize Thyroid Hormone: Iodine & Goitrogens 01:33:56 Peptides: Growth Hormone, Tesamorelin, Ibutamoren & Gut Microbiome 01:42:06 Testosterone Therapy 01:47:03 Prescriptions & Hormones: Human Choriogonadotropin (HCG), Clomiphene 01:52:56 Testosterone Therapy + HCG, Fertility & Temperature 01:55:30 Hormone Health Q&A: Marijuana, Nicotine, Cycling, Pelvic Floor, Alcohol, Fat 02:06:08 Prostate Health & Tadalafil, Prostate Specific Antigen (PSA) 02:09:56 Hair Loss & DHT; Turmeric & Curcuminoids 02:18:13 BPAs, Phthalates & Hormone Health 02:21:55 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media, Momentous, Neural Network Newsletter The Huberman Lab podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.