Science says eating just one meal per day can improve your health. Learn more at https://highintensityhealth.com/OMAD ----- Moises is author of the best selling book, An Epidemic of Absence: A New Way of Understanding Allergies and Autoimmune Diseases. He seems to have unearthed the reason why inflammatory diseases are so rampant today: our immune system has a broken off switch. Parasites used to be the “brakes” of our immune system. “We’ve outsourced our immune tolerance to them,” he says. (In order for parasites to thrive in our bodies, they tricked our immune system into thinking they weren’t there.) But, now they’re gone… Asthma, allergies, autoimmunity and neuroinflammatory diseases are on the rise. Parasites even make the microbiome more diverse, according to new research. Learn more: Moises is is the author of a best selling book on microbes called Epidemic of Absence. His research and book cleared up many missing links in my mind about immunology and microbes, I’m sure you’ll feel the same. Here are some key takeaways: 02:16 The Role of Parasitic Worms (Helminths): 06:20 T-Reg Cells as a Mechanism: 08:27 Parasites & Helminths and Hormone Regulation: Chronic infection is costly to the body’s energy stores to keep the immune system at strength. There is less energy to invest in other areas like procreation. In animal studies, as soon as a rat is infected with helminths, sex hormone levels drop. 12:31 How Did Humans Get So Clean? before it is evicted from our bodies. Crowd diseases came with agriculture and settled living. The past 15,000 years of human history has been a gradual buildup of pestilence and filth, which culminates in the industrial revolution with huge migration into cities with little to no sanitation. In the 19th century we began the sanitary revolution with sewers, clean water, and a basic understanding of germ theory. Suddenly this genome that had been exposed to ever increasing quantities of filth, parasite load and crowd diseases, 26:32 Hookworm Study: A small study of hookworms theorized that the pig whip worm was never meant to reside in the human body and would not work. 28:03 Parasites and the Gut Microbiome: The hookworm study also looked at changes in the gut microbiome. With the introduction of the hookworms, diversity of the microbiome increased. Generally people with celiac have an impoverished microbiome. When ecosystems are more diverse are generally healthier, more productive, less prone to disturbance or invasion. In rodent studies, helminth infection seems to increase diversity and increase metabolites (fermentation byproducts) of the microbiome that are thought to be healthy.