The gut and brain communicate via the vagus nerve to coordinate serotonin levels, which is crucial for mood.
“when you hear that most of the serotonin in your body is made in your gut, that's true, and it stays in your gut, but the levels of serotonin are communicated to the brain by the vagus, and then stimulates the release of serotonin from the dorsal raphe nucleus.”
Huberman Lab · Jun 2025 · 2 episodes · 983K views on this topicHe claims that his serotonin is derived from his phone and his dog.
“i'm a cave dwelling pizza eating non-exercising gremlin and i want to get my serotonin from like my cell phone and my dog”
Distractible Podcast · Apr 2022 · 1 episode · 345K views on this topicHe states that his sense of well-being, or serotonin balance, comes from the contentment and purpose he feels in his daily life.
“i do know that it generally in my life i am happy i am content and i feel like i have purpose which i think means that my neurotransmitters are in a good balance”
Distractible Podcast · Apr 2022 · 1 episode · 345K views on this topicExtracted by a model; may misattribute who said what.