Sign up to receive Peter's email newsletter: https://bit.ly/4c602k2 Original release date: 10/1/2018 In this episode, Richard Isaacson, a neurologist and director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and New York-Presbyterian, discusses strategies for staving off Alzheimer’s disease. Richard shares a wealth of insight for people who want to know more about Alzheimer’s and what you can do to help yourself and your loved ones — starting today and continuing throughout the entire lifespan. We discuss: -Richard’s fun-facts (and alter egos): “bling” phones, Doogie Howser, and DJ Rush [8:00]; -Richard’s impetus to focus on Alzheimer’s disease: Uncle Bob [18:20]; -Starting an Alzheimer’s Prevention Clinic [27:00]; -How Alzheimer’s is diagnosed [30:00]; -Short-term memory, processing speed, executive function, and how they’re tested [35:45]; -Prevention vs reduction of Alzheimer’s [44:00]; -What is the prevalence of Alzheimer’s in America? [49:30]; -How do people actually die from Alzheimer’s or dementia? [51:30]; -How can people do everything right and still get Alzheimer’s? It’s all about AGE [55:15]; -The APOE gene [58:15]; -Why is the risk of Alzheimer’s higher for women? [1:13:00]; -How many different paths lead to Alzheimer’s? [1:15:45]; -What role does MTHFR play in Alzheimer’s? [1:19:45]; -What are the “ABCs” of Alzheimer’s prevention? [1:26:45]; -Baptists, Tauists, Syners, and Apostates [1:36:30]; -Concerns with statin use for high-risk patients [1:45:00]; -The use of Theracurmin [1:48:45]; -What are the five actionable things one can do to reduce the risk for -Alzheimer’s today? [1:54:30]; -The cognitive reserve [2:14:15]; and -More. Show notes page: https://peterattiamd.com/richardisaacson/ About: The Peter Attia Drive is a weekly, ultra-deep-dive podcast focusing on maximizing health, longevity, critical thinking…and a few other things. With over 10 million episodes downloaded, it features topics including fasting, ketosis, Alzheimer’s disease, cancer, mental health, and much more. Peter is the founder of Attia Medical, PC, a medical practice with offices in San Diego and New York City, focusing on the applied science of longevity. The practice applies nutritional biochemistry, exercise physiology, sleep physiology, techniques to increase distress tolerance, lipidology, pharmacology, and four-system endocrinology to increase lifespan (delaying the onset of chronic disease), while simultaneously improving healthspan (quality of life). Learn more: https://peterattiamd.com/ Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Play: http://bit.ly/TheDriveGooglePlay