Lean, metabolically healthy individuals may experience significant increases in LDL cholesterol when adopting a low-carb diet as part of the Lipid Energy Model.

“what we see is actually the people with obesity and insulin resistance disorders they don't have LDL increases the people have increases are the lean healthy athletic ones so Dave observed this this was back in 2017 we didn't have hard data um he didn't have hard data I wasn't evening keto at the ti”

The CHORIBar improves cardiovascular health by shifting the HDL particle profile toward larger, healthier particles that facilitate reverse cholesterol transport.

“so what the Quarry bar does is it takes the profile and it shifts it towards the larger particle and that informs us that what the Quarry bar is doing it's helping to improve the activity of that HDL particles it's making it function better”

The brain's cholesterol metabolism operates entirely independently of the systemic peripheral system due to the blood-brain barrier.

“So the brain lipid and lipoprotein system that we're going to talk about has almost nothing to do with the plasma transportation of lipids and lipoproteins. And that is such a crucial concept that must be understood.”

Measuring HDL cholesterol and LDL cholesterol metrics provides no insight into the complex flux and trafficking of cholesterol pools in the body.

“and that's where the whole thing falls apart because those metrics have zero to do with describing the complex flux and trafficking of all these pools of cholesterol or so 0 there is no cholesterol measurement in the plasma that tells you anything about movement of that movement”