LDL cholesterol particle number serves as the primary driver of atherosclerosis, and lowering it is the essential strategy for preventing the disease.

“Once apo particles are not cleared there's only one other option for them they have to invade an artery wall. So it's the Apo B concentration and they deliver cholesterol and that explains aogenesis”

ApoB particle count is a more accurate metric for assessing cardiovascular risk than LDL cholesterol or HDL cholesterol.

“most people think it's an NMR measurement which it absolutely is not basically if you want that metric and we've already announced I do work for true health diagnostics I was working with a different lab before that the lab that actually did the development of the LP little a april-b assay”

ApoB particle concentration is a more accurate predictor of cardiovascular risk than LDL cholesterol.

“a better way to predict risk is to add up the concentration of all the apob particles”

ApoB is a superior metric compared to routine lipid panels for determining cardiovascular risk.

“there's no question that the number of LDL particles is a more accurate index of risk than the LDL cholesterol”

LDL particle number is a superior biomarker to LDL cholesterol for managing cardiovascular risk.

“In that case, it's very clear that LDLP or APOB is a better biomarker because a lot of people who achieve very low LDL cholesterol have not achieved equally very low LDL particles or APOB and they therefore with visibility to that would be candidates for more aggressive LDL lowering.”

He argues that while LDL is necessary for atherosclerosis, its role is contextual and should not be managed in isolation without considering overall metabolic health.

“I still think Applebe is quote causal, but that doesn't mean it's most important. It's the same with terms like evidence-based, quote unquote, and you know, best medicine.”

Lipoprotein levels are primarily influenced by energy metabolism and the body's need to transport fatty acids.

“I feel as if I've come across enough with my own mapping of my own metabolism that I found how I can move LDL cholesterol and LDL particle count up and down without medication or supplements by finding what I believe to be the primary influencer which is the energy metabolism”

The consumption of saturated fat in a diet that restricts carbohydrates does not lead to the accumulation of harmful fats in the body.

“this example of what happens when you consume saturated fat in the matrix of a diet that includes carbohydrate restriction is so against that long worn out idea of you are what you eat”