Cellular senescence serves as a protective mechanism against cancer by stopping the proliferation of damaged cells that could otherwise form tumors.

“There's tons of data that go back two decades or more showing that the arrest of cell proliferation is extremely important for preventing cancer. So that stressed cell is in danger of becoming a cancerous cell and the stress response intrinsic to the cell says, "No way, you will never divide again”

The primary strategy for cancer control is to avoid systemic factors that amplify existing cancer cells.

“So, yeah, the name of the game is avoid the amplifiers.”

Navdeep Chandel claims that mitochondrial function, particularly the TCA cycle and respiratory chain, is necessary for tumor growth.

“we genetically knocked out the respiratory chain so can respire so now it's 100% glycolysis it's exactly what a tumor that Warburg would love do you make bigger tumors according to him yes if it's all about glycolysis how do you make smaller tumors wait we made very smaller to him a little little ti”