Dr. Rhonda Patrick interviews Wim Hof also known as the "Iceman." Wim holds the world record for the longest ice bath (1 hour and 53 minutes and 12 seconds), just to name one of his many impressive feats. Dr. Patrick and Wim talk a bit about Wim's back story that culminated in him trying out cold water immersion, the relatively recent 2014 scientific publication of the “Wim Hof Method” which includes cold exposure during training, exposure to bacterial endotoxin, Wim's breathing techniques, and meditation (http://www.ncbi.nlm.nih.gov/pubmed/24799686). The 2014 study demonstrated the effects of just 4 days of training with the “Wim Hof method” on 12 volunteers injected with bacterial endotoxin. Some of the effects include: increased epinephrine, norepinephrine, increased anti-inflammatory cytokines (IL-10), decreased pro-inflammatory cytokines (TNF-alpha), increased blood ph to 7.75 (in some cases), and decreased carbon dioxide blood levels. The results of this study hint at some very interesting possibilities that might explain why Wim's technique helps him to endure the cold more, as well as how he was able to suppress his inflammatory response to endotoxin himself. EPISODE LINKS: Show notes and transcript: https://www.foundmyfitness.com/episodes/wim-hof?utm_source=youtube&utm_medium=youtube&utm_campaign=hof_interview Wim' Hof's website: http://www.innerfire.nl Wim Hof on Instagram: http://instagram.com/iceman_hof PODCAST INFO: Email: https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=hof_interview Apple Podcasts: https://podcasts.apple.com/us/podcast/foundmyfitness/id818198322?i=1000532219201 Spotify: https://open.spotify.com/episode/3qpdp9sAlkbagUMtokHoS6?si=DArKK763QtKijC4Bj71dyg&nd=1 Full interview playlist: https://www.youtube.com/playlist?list=PLJEEAVzHu9KzgkQbe2Thh35VU-HCiId_s Clips playlist: https://www.youtube.com/playlist?list=PLrGxo-5Uw8gI9-1IStYEvNxVukKxZBlmi Chapters 00:00:00 - Introduction 00:02:08 - Wim's cold story 00:09:32 - Cold response 00:14:37 - Breathing and pH 00:21:43 - Endotoxin 00:24:50 - Love 00:26:42 - Primordial drives 00:30:23 - Meditation 00:32:23 - Oxygenation 00:37:34 - Brain and Mind 00:44:47 - Van Gogh's cold therapy About FoundMyFitness: Rhonda Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, and St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California, San Diego. She has done extensive research on aging, cancer, and nutrition. It is Dr. Patrick’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach. Learn more about Dr. Rhonda Patrick and her mission for FoundMyFitness at www.foundmyfitness.com?utm_source=youtube&utm_medium=youtube&utm_campaign=hof_interview About Wim Hof: After depression led to his wife's untimely death, Wim Hof dedicated his life pursuit to finding natural ways to "hack" the physiological system. His studies into various ancient traditions led him to explore the effects of controlled breathing on the body and mind, especially in response to cold shock. In a 2018 study where Wim underwent MRI scans to examine his brain activity, researchers found that Wim is able to induce a meditative state of euphoria by engaging the central nervous system with his controlled breathing exercise, the Wim Hof method, allowing him to withstand perilous exposures to the cold and actually raise his core body temperature. In effect, his lifework has served to give notable credence to the phrase, "mind over matter."(https://www.sciencedirect.com/science/article/abs/pii/S1053811918300673?via%3Dihub#!) SCIENCE OF HEALTHSPAN EMAIL NEWSLETTER: Receive emailed episode notifications and regular updates on the emerging science of healthspan. https://www.foundmyfitness.com/newsletter?utm_source=youtube&utm_medium=youtube&utm_campaign=hof_interview SUPPORT THE CHANNEL: Many of the magnificent resources associated with the FoundMyFitness channel exist directly as a result of our premium membership. As a premium member, listeners get access to our exclusive podcast The Aliquot, monthly Q&As, a special summary of scientific research every other week called the Science Digest, and more. Sign up to become a premium member and nurture the existence of all of the otherwise free resources provided by FoundMyFitness at https://www.foundmyfitness.com/crowdsponsor?utm_source=youtube&utm_medium=youtube&utm_campaign=hof_interview Thank you for watching! SOCIALS: https://twitter.com/foundmyfitness https://facebook.com/foundmyfitness https://instagram.com/foundmyfitness PODCAST: Apple Podcasts: https://podcasts.apple.com/us/podcast/foundmyfitness/id818198322 Spotify: https://open.spotify.com/show/5QjpaU0o1Q2MkVZwwG3y7d #wimhofmethod #controlledbreathing #coldshock