ApoB particle concentration is a more accurate predictor of cardiovascular risk than LDL cholesterol.

“a better way to predict risk is to add up the concentration of all the apob particles”

Dietary cholesterol has a negligible effect on blood cholesterol levels in the general population.

“when I went through the literature, I was just astonished that how small the effect is, and it's very difficult to even imagine how an effect of excess dietary cholesterol couldn't influence heart disease risk unless when you either had a mutation that caused the cholesterol to build up”

He believes the only two blood measurements required to assess risk for atherosclerosis are apob and triglycerides.

“personally I believe the only things you need to measure in the blood are apob and triglycerides”

He argues that while LDL is necessary for atherosclerosis, its role is contextual and should not be managed in isolation without considering overall metabolic health.

“I still think Applebe is quote causal, but that doesn't mean it's most important. It's the same with terms like evidence-based, quote unquote, and you know, best medicine.”

Cholesterol is a vital factor in the diet necessary for brain function, hormone production, and protection from disease.

“It's necessary for your proper brain function and nervous system and protection from disease”