Atherogenic dyslipidemia, which involves high triglycerides, low HDL, and small LDL particles, is a major marker of heart disease risk.

“it's this metabolic trait, atherogenic dyslipidemia, of which the small LDL is a marker for and is almost certainly a causative feature of the disease associated with risk.”

Standard lipid metrics like HDL cholesterol are often insufficient for predicting risk compared to functional assays.

“I think it's pretty well established at this point that this so-called cholesterol reflex capacity measurement of HDL is a better marker or predictor of risk than just measuring HDL cholesterol consistent with the idea that function is important”

The belief that large LDL particles are benign is a fallacious idea.

“So this idea that somehow fluffy large LDL particles are not to worry about or benign is completely facious.”

The causal relationship between LDL and atherosclerosis is not a foregone conclusion, especially for those with high HDL and low triglycerides.

“you've probably also heard the Davis somewhat skeptical of the LDL is causal paradigm more thinking in atherosclerosis so you're probably understand that out of the gate Dave and I don't really see eye to eye on the genesis of heart disease”

Elevated LDL cholesterol is the primary driver of atherosclerotic cardiovascular disease.

“for me it is so simple because these people have one thing one a mutation in a single Gene that doesn't do anything else then raise LDL cholesterol and they drop dead you know when they're like 25. so for me I don't even listen to it anymore”

The trapping of apoB-containing lipoproteins within the arterial wall is the fundamental causal factor of atherosclerosis.

“any cholesterol in the artery only got there within an apob particle it doesn't just float in it gets there within an apob particle either vld or ldl that gets into the arterial wall and gets stuck there that's the cause of atherosclerosis”

He asserts that atherosclerosis is defined solely by the presence of cholesterol in the artery wall.

“I always joke there's like one synanon for aerosis and that says do you have cholesterol in your artery wall or do you not if you don't you don't have aosc orotic heart disease”

Dr. Roy states that COVID-19 is known to cause cardiovascular issues like myocarditis and blood clots, whereas vaccines have not been shown to cause cardiac arrest.

“the studies are very clear that coid 19 or the SARS K2 virus has been shown to cause cardiac problems but not the vaccines”

Myocarditis risk is significantly higher following a SARS-CoV-2 infection than it is from receiving a COVID-19 vaccine.

“this pre-print non-peer reviewed article using electronic records in the United States, also agreed with the Israeli data that was published in the new England journal of medicine and came to the conclusion that young males infected with the virus are up to six times more likely to develop myocardit”