Atherosclerotic cardiovascular disease is primarily and causally driven by the accumulation of LDL or apoB particles in the artery wall.
3 people · 3 episodes
Elevated LDL cholesterol is the primary driver of atherosclerotic cardiovascular disease.
“for me it is so simple because these people have one thing one a mutation in a single Gene that doesn't do anything else then raise LDL cholesterol and they drop dead you know when they're like 25. so for me I don't even listen to it anymore”
The Peter Attia Drive · May 2023 · 1 episode · 30K views on this topicThe trapping of apoB-containing lipoproteins within the arterial wall is the fundamental causal factor of atherosclerosis.
“any cholesterol in the artery only got there within an apob particle it doesn't just float in it gets there within an apob particle either vld or ldl that gets into the arterial wall and gets stuck there that's the cause of atherosclerosis”
The Peter Attia Drive · Nov 2021 · 2 episodes · 690K views on this topicHe asserts that atherosclerosis is defined solely by the presence of cholesterol in the artery wall.
“I always joke there's like one synanon for aerosis and that says do you have cholesterol in your artery wall or do you not if you don't you don't have aosc orotic heart disease”
The Peter Attia Drive · Feb 2025 · 5 episodes · 349K views on this topicThe causal link between LDL and cardiovascular disease is not fully established or relies on overly simplistic metrics of lipid particles.
3 people · 3 episodes
Atherogenic dyslipidemia, which involves high triglycerides, low HDL, and small LDL particles, is a major marker of heart disease risk.
“it's this metabolic trait, atherogenic dyslipidemia, of which the small LDL is a marker for and is almost certainly a causative feature of the disease associated with risk.”
FoundMyFitness · Oct 2015 · 1 episode · 542K views on this topicThe belief that large LDL particles are benign is a fallacious idea.
“So this idea that somehow fluffy large LDL particles are not to worry about or benign is completely facious.”
The Peter Attia Drive · Aug 2026 · 1 episode · 20K views on this topicThe causal relationship between LDL and atherosclerosis is not a foregone conclusion, especially for those with high HDL and low triglycerides.
“you've probably also heard the Davis somewhat skeptical of the LDL is causal paradigm more thinking in atherosclerosis so you're probably understand that out of the gate Dave and I don't really see eye to eye on the genesis of heart disease”
The Peter Attia Drive · Jan 2020 · 1 episode · 15K views on this topicCardiovascular complications like myocarditis are significantly more likely to arise from SARS-CoV-2 infection than from vaccination.
2 people · 2 episodes
Dr. Roy states that COVID-19 is known to cause cardiovascular issues like myocarditis and blood clots, whereas vaccines have not been shown to cause cardiac arrest.
“the studies are very clear that coid 19 or the SARS K2 virus has been shown to cause cardiac problems but not the vaccines”
StarTalk · Nov 2023 · 1 episode · 414K views on this topicMyocarditis risk is significantly higher following a SARS-CoV-2 infection than it is from receiving a COVID-19 vaccine.
“this pre-print non-peer reviewed article using electronic records in the United States, also agreed with the Israeli data that was published in the new England journal of medicine and came to the conclusion that young males infected with the virus are up to six times more likely to develop myocardit”
FoundMyFitness · Sep 2021 · 1 episode · 221K views on this topicExtracted by a model; may misattribute who said what.
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